Prenol lipids
Medchemexpress LLC Cucurbitacin IIa | 58546-34-2 | 562.73 | 1 MG
Cucurbitacin IIa, also known as Hemslecin A, is an orally active EGFR inhibitor capable of permeating the blood-brain barrier. It demonstrates an IC50 of 1.455 nM against human EGFR and exhibits anti-inflammatory activity by inhibiting the EGFR-MAPK signaling pathway.
Features and Benefits:
- Induces caspase-3-dependent apoptosis.
- Downregulates survivin expression.
- Enhances autophagy levels.
- Disrupts the actin cytoskeleton via actin aggregation.
- Arrests the cell cycle at the G2/M phase.
- Supports research into inflammation-related diseases.
- Useful in studies on depression and cancers like non-small cell lung cancer.
Medchemexpress LLC TANSHINONE IIA, 50 MG
MedChemExpress LLC| Tanshinone IIA | 50 mg | HY-N0135 | Purity 99.74% | 568-72-9 | MW: 294.34
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g/mol | C14H14O4S | 5 MG
This bisphenol-derived small-molecule inhibits DNA topoisomerase II alpha and is intended for research use. It demonstrates topo II inhibitory activity and in vitro cell growth inhibition, making it suitable for biochemical and anticancer studies.
- Small-molecule inhibitor of DNA topoisomerase II alpha.
- Bisphenol-derived structure; formula C14H14O4S.
- Documented in vitro topo II inhibitory activity and cell growth IC50 values.
- Supplied in small quantities for research use (5 mg pack).
- Intended for biochemical and anticancer research applications.
Selleck Chemical LLC Tanshinone IIA 50mg 568-72-9 Tanshinone B
Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 278.32 g/mol | C14H14O4S | 10 MG
Topoisomerase IIα-IN-9 (4,4'-sulfonylbis(2-methylphenol)) is a bisphenol compound that moderately inhibits human DNA topoisomerase II and reduces cell proliferation in selected cell lines. It is supplied for laboratory research; lot-specific purity, solubility, and storage conditions are provided in the product data sheet and Certificate of Analysis.
- Moderate topoisomerase II inhibition (IC50: 571 μM).
- Inhibits K562 cell growth (IC50: 117 μM) and CHO cell growth (IC50: 218 μM).
- Molecular weight 278.32 g/mol and formula C14H14O4S.
- CAS number 16346-97-7 for unambiguous identification.
- Intended for research use; consult Certificate of Analysis for purity and storage.
Apexbio Technology LLC Cryptotanshinone 35825-57-1 20mg
Cryptotanshinone (CAS 35825-57-1) is a bioactive diterpene quinone derived from Salvia miltiorrhiza It modulates cellular signaling pathways by interacting with various molecular targets including components of the STAT3 signaling cascade thereby influencing transcriptional activity Studies indicate that cryptotanshinone alters gene expression profiles associated with cellular stress responses and apoptosis Due to its ability to regulate molecular pathways relevant to cancer biology and oxidative stress cryptotanshinone is widely utilized in biomedical research investigating mechanisms of tumor progression chemoprevention and cytoprotection
Medchemexpress LLC RI-AG03 acetate | 98.2% | 2477.93 | 5 MG
RI-AG03 acetate is the acetate of RI-AG03, an orally active and BBB-penetrable Tau aggregation peptide inhibitor. It inhibits Tau aggregation and improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models. This product can be used in the study of tauopathies such as Alzheimer's disease.
- Orally active
- BBB-penetrable Tau aggregation peptide inhibitor
- Inhibits Tau aggregation
- Improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models
- Can be used in the study of tauopathies such as Alzheimer's disease
Medchemexpress LLC Temporin B (acetate) | 99.0% | 1511.89 | 5 MG
Temporin B acetate is an antimicrobial peptide effective against Gram-positive bacteria, with less activity against Gram-negative bacteria.
- Antimicrobial peptide
- Effective against Gram-positive bacteria
- Less active against Gram-negative bacteria
- Store in sealed container, away from moisture
- Powder can be stored at -80°C for 2 years or -20°C for 1 year
- In solvent, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC sGnRH-A acetate | 99.9% | 1342.50 | 5 MG
sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. It stimulates growth hormone secretion and can also be used as an inducer of ovulation by artificial insemination. This product is intended for research use only.
- Increases GH mRNA levels
- Stimulates GH secretion in a dose-dependent manner
- Induces growth hormone levels in common carp pituitary fragments
- Serves as an inducer of ovulation by artificial insemination
- Intended for research use only
Medchemexpress LLC Vitamin D Receptor/V 50ug
Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag